M B Youdim Selected Research

(N-propargyl-(3R) and (3S) aminoindan-5-yl)-ethyl methyl carbamate

12/2001	Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate].
1/2000	TV3326, a novel neuroprotective drug with cholinesterase and monoamine oxidase inhibitory activities for the treatment of Alzheimer's disease.

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M B Youdim Research Topics

Disease

14	Parkinson Disease (Parkinson's Disease) 10/2001 - 01/2000
9	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2001 - 01/2000
5	Alzheimer Disease (Alzheimer's Disease) 01/2006 - 01/2000
4	Neuroblastoma 01/2006 - 01/2000
3	Ischemia 12/2001 - 01/2000
3	Closed Head Injuries 06/2001 - 01/2000
2	Iron Deficiencies 05/2000 - 01/2000
2	Neoplasms (Cancer) 04/2000 - 01/2000
2	Acquired Immunodeficiency Syndrome (AIDS) 04/2000 - 01/2000
1	Glioblastoma (Glioblastoma Multiforme) 01/2006
1	Nervous System Diseases (Neurological Disorders) 01/2006
1	Inflammation (Inflammations) 07/2001
1	Brain Edema (Cerebral Edema) 06/2001
1	Pheochromocytoma 06/2001
1	Body Weight (Weight, Body) 01/2001
1	MPTP Poisoning 01/2001
1	Parkinsonian Disorders (Parkinsonism) 01/2001
1	Epilepsy (Aura) 06/2000
1	Necrosis 04/2000
1	Obesity 03/2000
1	Schizophrenia (Dementia Praecox) 03/2000

Drug/Important Bio-Agent (IBA)

8	Neuroprotective AgentsIBA 06/2001 - 01/2000
7	IronIBA 01/2006 - 01/2000
7	Monoamine Oxidase (MAO)IBA 06/2001 - 01/2000
6	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 09/2001 - 01/2000
5	rasagiline (Azilect)FDA Link 12/2001 - 01/2001
4	NeurotoxinsIBA 12/2001 - 01/2000
3	(N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamateIBA 12/2001 - 01/2000
3	Cholinesterases (Cholinesterase)IBA 12/2001 - 01/2000
3	AntioxidantsIBA 09/2001 - 01/2000
3	Selegiline (E250)FDA LinkGeneric 01/2001 - 01/2000
2	ZincIBA 01/2006 - 06/2000
2	CopperIBA 01/2006 - 01/2001
2	Chelating AgentsIBA 01/2006 - 06/2000
2	(N-propargyl-(3R) and (3S) aminoindan-5-yl)-ethyl methyl carbamateIBA 12/2001 - 01/2000
2	Nerve Growth Factors (Neurotrophins)IBA 07/2001 - 04/2000
2	Apomorphine FDA Link 07/2001 - 01/2000
2	CytokinesIBA 01/2001 - 04/2000
2	Transcription Factors (Transcription Factor)IBA 01/2001 - 04/2000
2	Dopamine (Intropin)FDA LinkGeneric 05/2000 - 01/2000
1	5' Untranslated Regions (5' UTR)IBA 01/2006
1	Toxic ActionsIBA 01/2006
1	Amyloid (Amyloid Fibrils)IBA 12/2001
1	methyl carbamateIBA 12/2001
1	N-propargylIBA 12/2001
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 12/2001
1	CarbamatesIBA 12/2001
1	Proteins (Proteins, Gene)FDA Link 12/2001
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2001
1	TeaIBA 09/2001
1	PolyphenolsIBA 09/2001
1	Complementary DNA (cDNA)IBA 07/2001
1	Glutamic Acid (Glutamate)FDA Link 07/2001
1	Rivastigmine (Exelon)FDA LinkGeneric 06/2001
1	Oxygen (Dioxygen)IBA 06/2001
1	Glucose (Dextrose)FDA LinkGeneric 06/2001
1	Nerve Growth Factor (NGF)IBA 06/2001
1	CalbindinsIBA 01/2001
1	Superoxide Dismutase-1IBA 01/2001
1	Amphetamine (Amfetamine)FDA LinkGeneric 01/2001
1	Calcium-Binding ProteinsIBA 01/2001
1	Ferritins (Ferritin)IBA 01/2001
1	Glutathione (Reduced Glutathione)IBA 01/2001
1	Levodopa (L Dopa)FDA LinkGeneric 01/2001
1	LipofuscinIBA 01/2001
1	Melanins (Melanin)IBA 01/2001
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2001
1	Transferrin Receptors (Transferrin Receptor)IBA 01/2001
1	Sympathomimetics (Sympathomimetic Amines)IBA 01/2001
1	Transferrin (beta 2 Transferrin)IBA 01/2001
1	TyramineIBA 01/2001
1	VitaminsIBA 01/2001
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 01/2001
1	UbiquitinIBA 01/2001
1	Heme Oxygenase-1IBA 01/2001
1	neuromelaninIBA 01/2001
1	Kainic Acid (Kainate)IBA 06/2000
1	Opiate AlkaloidsIBA 05/2000
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 04/2000
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2000
1	InterleukinsIBA 04/2000
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 04/2000
1	Interleukin-6 (Interleukin 6)IBA 04/2000
1	Insulin-Like Growth Factor I (IGF-1)IBA 03/2000
1	Fluvoxamine (Luvox)FDA LinkGeneric 03/2000
1	Pergolide (Permax)FDA Link 01/2000
1	Oxidopamine (6 Hydroxydopamine)IBA 01/2000
1	Cyclooxygenase InhibitorsIBA 01/2000
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2000
1	LisurideIBA 01/2000
1	Dopamine Agonists (Dopamine Agonist)IBA 01/2000
1	salsolineIBA 01/2000
1	SteroidsIBA 01/2000
1	EnkephalinsIBA 01/2000

Therapy/Procedure

4	Therapeutics 01/2001 - 01/2000
1	Analgesia 01/2000